Sensitive and Direct Detection of Receptor Binding Specificity of Highly Pathogenic Avian Influenza A Virus in Clinical Samples

Influenza A virus (IAV) recognizes two types of N-acetylneuraminic acid (Neu5Ac) by galactose (Gal) linkages, Neu5Acα2,3Gal and Neu5Acα2,6Gal. Avian IAV preferentially binds to Neu5Acα2,3Gal linkage, while human IAV preferentially binds to Neu5Acα2,6Gal linkage, as a virus receptor. Shift in recepto...

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Detalhes bibliográficos
Main Authors: Takahashi, Tadanobu, Kawakami, Tatsuya, Mizuno, Takashi, Minami, Akira, Uchida, Yuko, Saito, Takehiko, Matsui, Shigeyuki, Ogata, Makoto, Usui, Taichi, Sriwilaijaroen, Nongluk, Hiramatsu, Hiroaki, Suzuki, Yasuo, Suzuki, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799784/
https://ncbi.nlm.nih.gov/pubmed/24205123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078125
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