Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE)

Motivation: Identifying the cellular wiring that connects genomic perturbations to transcriptional changes in cancer is essential to gain a mechanistic understanding of disease initiation, progression and ultimately to predict drug response. We have developed a method called Tied Diffusion Through I...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Paull, Evan O., Carlin, Daniel E., Niepel, Mario, Sorger, Peter K., Haussler, David, Stuart, Joshua M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2013
Gaiak:
Original Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799471/
https://ncbi.nlm.nih.gov/pubmed/23986566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt471
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