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FDG-PET as a predictive biomarker for therapy with everolimus in metastatic renal cell cancer

The mTOR (mammalian target of rapamycin) inhibitor, everolimus, affects tumor growth by targeting cellular metabolic proliferation pathways and delays renal cell carcinoma (RCC) progression. Preclinical evidence suggests that baseline elevated tumor glucose metabolism as quantified by FDG-PET ([(18)...

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Detalhes bibliográficos
Main Authors: Chen, James L, Appelbaum, Daniel E, Kocherginsky, Masha, Cowey, Charles L, Kimryn Rathmell, Wendy, McDermott, David F, Stadler, Walter M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799289/
https://ncbi.nlm.nih.gov/pubmed/24156027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.102
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