PTEN expression is consistent in colorectal cancer primaries and metastases and associates with patient survival

Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) negatively regulates the phosphoinositide-3-kinase (PI3K) signaling pathway. In colorectal cancer (CRC), observed frequencies of loss of PTEN expression, concordant expression in primary tumors and metastases, and the association of PT...

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Main Authors: Atreya, Chloe E, Sangale, Zaina, Xu, Nafei, Matli, Mary R, Tikishvili, Eliso, Welbourn, William, Stone, Steven, Shokat, Kevan M, Warren, Robert S
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2013
Teme:
Clinical Cancer Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799284/
https://ncbi.nlm.nih.gov/pubmed/24156022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.97
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