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Inactivated Rabies Vaccine Produced from the Flury LEP Strain of Virus Grown in BHK-21 Suspension Cells

Suspension cultures of BHK-21 cells maintained at 32 to 33 C were infected with the Flury LEP strain of rabies virus. By using a cell concentration of 2.0 × 10(6) to 2.5 × 10(6) cells per ml infected at a multiplicity of 0.05, high titers of extracellular virus were reached in 96 to 120 h, and poten...

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Bibliographic Details
Main Authors: Chapman, W. G., Ramshaw, I. A., Crick, Joan
Format: Artigo
Language:Inglês
Published: 1973
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC379922/
https://ncbi.nlm.nih.gov/pubmed/4588193
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