Rimonabant Precipitates Anxiety in Rats Withdrawn from Palatable Food: Role of the Central Amygdala

The anti-obesity medication rimonabant, an antagonist of cannabinoid type-1 (CB(1)) receptor, was withdrawn from the market because of adverse psychiatric side effects, including a negative affective state. We investigated whether rimonabant precipitates a negative emotional state in rats withdrawn...

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Bibliographische Detailangaben
Hauptverfasser: Blasio, Angelo, Iemolo, Attilio, Sabino, Valentina, Petrosino, Stefania, Steardo, Luca, Rice, Kenner C, Orlando, Pierangelo, Iannotti, Fabio Arturo, Di Marzo, Vincenzo, Zorrilla, Eric P, Cottone, Pietro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799070/
https://ncbi.nlm.nih.gov/pubmed/23793355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.153
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