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Temporal Pattern of Cocaine Intake Determines Tolerance vs Sensitization of Cocaine Effects at the Dopamine Transporter

The dopamine transporter (DAT) is responsible for terminating dopamine (DA) signaling and is the primary site of cocaine's reinforcing actions. Cocaine self-administration has been shown previously to result in changes in cocaine potency at the DAT. To determine whether the DAT changes associat...

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Detalhes bibliográficos
Main Authors: Calipari, Erin S, Ferris, Mark J, Zimmer, Benjamin A, Roberts, David CS, Jones, Sara R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799057/
https://ncbi.nlm.nih.gov/pubmed/23719505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.136
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