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A role for IRF4 in the development of CLL

Interferon regulatory factor 4 (IRF4) is a critical transcriptional regulator of B-cell development and function. A recent genome-wide single-nucleotide polymorphism (SNP) association study identified IRF4 as a major susceptibility gene in chronic lymphocytic leukemia (CLL). Although the SNPs locate...

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Détails bibliographiques
Auteurs principaux: Shukla, Vipul, Ma, Shibin, Hardy, Richard R., Joshi, Shantaram S., Lu, Runqing
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798999/
https://ncbi.nlm.nih.gov/pubmed/23926303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-492769
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