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From a marine neuropeptide to antimicrobial pseudopeptides containing aza-β(3)-amino acids: structure and activity
Incorporation of aza-β(3)-amino acids into endogenous neuropeptide from mollusks (ALSGDAFLRF-NH(2)) with weak antimicrobial activities allows us to design new AMPs sequences. We find that, depending on the nature of the substitution, these could result either in inactive pseudopeptides or in a drast...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical Society
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798980/ https://ncbi.nlm.nih.gov/pubmed/22320306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm2011595 |
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