The in situ local immune response, tumour senescence and proliferation in colorectal cancer

BACKGROUND: Immune cell infiltrates are important determinants of colorectal cancer (CRC) outcome. Their presence may be driven by tumour or host-specific factors. From previous studies in mice, senescence, a state of cell cycle arrest, may moderate tumour progression through upregulation of antitum...

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Hlavní autoři: Roxburgh, C S, Richards, C H, MacDonald, A I, Powell, A G, McGlynn, L M, McMillan, D C, Horgan, P G, Edwards, J, Shiels, P G
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
Molecular Diagnostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798960/
https://ncbi.nlm.nih.gov/pubmed/24022192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.556
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