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Transforming growth factor-β1 impairs CFTR-mediated anion secretion across cultured porcine vas deferens epithelial monolayer via the p38 MAPK pathway

The goal of this study was to determine whether transforming growth factor-β1 (TGF-β1) affects epithelial cells lining the vas deferens, an organ that is universally affected in cystic fibrosis male patients. In PVD9902 cells, which are derived from porcine vas deferens epithelium, TGF-β1 exposure s...

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Hlavní autoři: Yi, Sheng, Pierucci-Alves, Fernando, Schultz, Bruce D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798679/
https://ncbi.nlm.nih.gov/pubmed/23903699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00121.2013
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