The APE1 Asp/Asp Genotype and the Combination of APE1 Asp/Asp and hOGG1-Cys Variants Are Associated With Increased p53 Mutation in Non–Small Cell Lung Cancer

BACKGROUND: The hOGG1 Ser326Cys polymorphism is associated with lung cancer risk, but there are limited data regarding an association between the APE1 Asp148Glu polymorphism and lung cancer. Biological evidence shows that the hOGG1-Cys allele results in less DNA repair activity; however, this is not...

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Bibliographische Detailangaben
Hauptverfasser: Lin, Chun-Hsuan, Chen, Po-Ming, Cheng, Ya-Wen, Chen, Chih-Yi, Yuan, Chiun-Jye, Lee, Huei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Japan Epidemiological Association 2012
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798566/
https://ncbi.nlm.nih.gov/pubmed/23038158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2188/jea.JE20120048
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