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Transgenic Expression of MicroRNA-185 Causes a Developmental Arrest of T Cells by Targeting Multiple Genes Including Mzb1

miR-185 is a microRNA (miR) that targets Bruton's tyrosine kinase in B cells, with reductions in miR-185 linked to B cell autoantibody production. In hippocampal neurons, miR-185 targets both sarcoplasmic/endoplasmic reticulum calcium ATPase 2 and a novel Golgi inhibitor. This miR is haploinsuf...

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Bibliografiske detaljer
Main Authors: Belkaya, Serkan, Murray, Sean E., Eitson, Jennifer L., de la Morena, M. Teresa, Forman, James A., van Oers, Nicolai S. C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798545/
https://ncbi.nlm.nih.gov/pubmed/24014023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.503532
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