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How a CCA Sequence Protects Mature tRNAs and tRNA Precursors from Action of the Processing Enzyme RNase BN/RNase Z

In many organisms, 3′ maturation of tRNAs is catalyzed by the endoribonuclease, RNase BN/RNase Z, which cleaves after the discriminator nucleotide to generate a substrate for addition of the universal CCA sequence. However, tRNAs or tRNA precursors that already contain a CCA sequence are not cleaved...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dutta, Tanmay, Malhotra, Arun, Deutscher, Murray P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
RNA
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798534/
https://ncbi.nlm.nih.gov/pubmed/24022488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.514570
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