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Factor V Activator from Daboia russelli russelli Venom Destabilizes β-Amyloid Aggregate, the Hallmark of Alzheimer Disease

Formation of plaque by fibrils of β-amyloid (Aβ) peptide in the brain is the characteristic feature of Alzheimer disease (AD). Inhibition of the process of aggregate formation from Aβ-monomer and destabilization of the aggregate could be useful for prevention and propagation of the disease respectiv...

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Detalhes bibliográficos
Main Authors: Bhattacharjee, Payel, Bhattacharyya, Debasish
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798527/
https://ncbi.nlm.nih.gov/pubmed/23986449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.511410
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