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Active and Accurate trans-Translation Requires Distinct Determinants in the C-terminal Tail of SmpB Protein and the mRNA-like Domain of Transfer Messenger RNA (tmRNA)

Unproductive ribosome stalling in eubacteria is resolved by the actions of SmpB protein and transfer messenger (tm) RNA. We examined the functional significance of conserved regions of SmpB and tmRNA to the trans-translation process. Our investigations reveal that the N-terminal 20 residues of SmpB,...

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Autores principales: Camenares, Devin, Dulebohn, Daniel P., Svetlanov, Anton, Karzai, A. Wali
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798523/
https://ncbi.nlm.nih.gov/pubmed/23986442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.503896
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