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Characterization of the AtsR Hybrid Sensor Kinase Phosphorelay Pathway and Identification of Its Response Regulator in Burkholderia cenocepacia

AtsR is a membrane-bound hybrid sensor kinase of Burkholderia cenocepacia that negatively regulates quorum sensing and virulence factors such as biofilm production, type 6-secretion, and protease secretion. Here we elucidate the mechanism of AtsR phosphorelay by site-directed mutagenesis of predicte...

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Bibliografiske detaljer
Main Authors: Khodai-Kalaki, Maryam, Aubert, Daniel F., Valvano, Miguel A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798511/
https://ncbi.nlm.nih.gov/pubmed/24014026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.489914
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