Extracellular Norepinephrine Clearance by the Norepinephrine Transporter Is Required for Skeletal Homeostasis

Changes in bone remodeling induced by pharmacological and genetic manipulation of β-adrenergic receptor (βAR) signaling in osteoblasts support a role of sympathetic nerves in the regulation of bone remodeling. However, the contribution of endogenous sympathetic outflow and nerve-derived norepinephri...

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Bibliographic Details
Main Authors: Ma, Yun, Krueger, Jessica J., Redmon, Sara N., Uppuganti, Sasidhar, Nyman, Jeffry S., Hahn, Maureen K., Elefteriou, Florent
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798479/
https://ncbi.nlm.nih.gov/pubmed/24005671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.481309
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