The Transcriptional Repressor Domain of Gli3 Is Intrinsically Disordered

The transcription factor Gli3 is acting mainly as a transcriptional repressor in the Sonic hedgehog signal transduction pathway. Gli3 contains a repressor domain in its N-terminus from residue G106 to E236. In this study we have characterized the intracellular structure of the Gli3 repressor domain...

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Main Authors: Tsanev, Robert, Vanatalu, Kalju, Jarvet, Jüri, Tanner, Risto, Laur, Kristi, Tiigimägi, Piret, Kragelund, Birthe B., Østerlund, Torben, Kogerman, Priit
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798401/
https://ncbi.nlm.nih.gov/pubmed/24146948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076972
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