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Breast Tumors with Elevated Expression of 1q Candidate Genes Confer Poor Clinical Outcome and Sensitivity to Ras/PI3K Inhibition

Genomic aberrations are common in cancers and the long arm of chromosome 1 is known for its frequent amplifications in breast cancer. However, the key candidate genes of 1q, and their contribution in breast cancer pathogenesis remain unexplored. We have analyzed the gene expression profiles of 1635...

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Auteurs principaux: Muthuswami, Muthulakshmi, Ramesh, Vignesh, Banerjee, Saikat, Viveka Thangaraj, Soundara, Periasamy, Jayaprakash, Bhaskar Rao, Divya, Barnabas, Georgina D., Raghavan, Swetha, Ganesan, Kumaresan
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798322/
https://ncbi.nlm.nih.gov/pubmed/24147022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077553
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