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De Novo ORFs in Drosophila Are Important to Organismal Fitness and Evolved Rapidly from Previously Non-coding Sequences

How non-coding DNA gives rise to new protein-coding genes (de novo genes) is not well understood. Recent work has revealed the origins and functions of a few de novo genes, but common principles governing the evolution or biological roles of these genes are unknown. To better define these principles...

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Detalhes bibliográficos
Main Authors: Reinhardt, Josephine A., Wanjiru, Betty M., Brant, Alicia T., Saelao, Perot, Begun, David J., Jones, Corbin D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798262/
https://ncbi.nlm.nih.gov/pubmed/24146629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003860
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