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Targeting miRNA-based medicines to cystic fibrosis airway epithelial cells using nanotechnology

Cystic fibrosis (CF) is an inherited disorder characterized by chronic airway inflammation. microRNAs (miRNAs) are endogenous small RNAs which act on messenger (m) RNA at a post transcriptional level, and there is a growing understanding that altered expression of miRNA is involved in the CF phenoty...

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Autors principals: McKiernan, Paul J, Cunningham, Orla, Greene, Catherine M, Cryan, Sally-Ann
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798151/
https://ncbi.nlm.nih.gov/pubmed/24143095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S47551
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