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p53 Regulates Period2 Expression and the Circadian Clock

The mechanistic interconnectivity between circadian regulation and the genotoxic stress response remains poorly understood. Here we show that the expression of Period 2 (Per2), a circadian regulator, is directly regulated by p53 binding to a response element in the Per2 promoter. This p53 response e...

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Detalles Bibliográficos
Main Authors: Miki, Takao, Matsumoto, Tomoko, Zhao, Zhaoyang, Lee, Cheng Chi
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798035/
https://ncbi.nlm.nih.gov/pubmed/24051492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3444
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