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Expression of the phagocytosis-essential protein TREM2 is down-regulated by an aluminum-induced miRNA-34a in a murine microglial cell line

One of the key classical pathological features of Alzheimer’s disease (AD) is the progressive accumulation of amyloid beta (Aβ42) peptides and their coalescence into highly insoluble senile plaque cores. A major factor driving Aβ42 peptide accumulation is the inability of brain cells to effectively...

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Detalhes bibliográficos
Main Authors: Alexandrov, Peter N., Zhao, Yuhai, Jones, Brandon M., Bhattacharjee, Surjyadipta, Lukiw, Walter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797872/
https://ncbi.nlm.nih.gov/pubmed/23778113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2013.05.010
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