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Identification of Cisplatin-Regulated Metabolic Pathways in Pluripotent Stem Cells

The chemotherapeutic compound, cisplatin causes various kinds of DNA lesions but also triggers other pertubations, such as ER and oxidative stress. We and others have shown that treatment of pluripotent stem cells with cisplatin causes a plethora of transcriptional and post-translational alterations...

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Detalhes bibliográficos
Main Authors: von Stechow, Louise, Ruiz-Aracama, Ainhoa, van de Water, Bob, Peijnenburg, Ad, Danen, Erik, Lommen, Arjen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797786/
https://ncbi.nlm.nih.gov/pubmed/24146875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076476
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