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Identification of Cisplatin-Regulated Metabolic Pathways in Pluripotent Stem Cells
The chemotherapeutic compound, cisplatin causes various kinds of DNA lesions but also triggers other pertubations, such as ER and oxidative stress. We and others have shown that treatment of pluripotent stem cells with cisplatin causes a plethora of transcriptional and post-translational alterations...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797786/ https://ncbi.nlm.nih.gov/pubmed/24146875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076476 |
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