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Flucytosine and cryptococcosis: time to urgently address the worldwide accessibility of a 50-year-old antifungal

Current, widely accepted guidelines for the management of HIV-associated cryptococcal meningoencephalitis (CM) recommend amphotericin B combined with flucytosine (5-FC) for ≥2 weeks as the initial induction treatment of choice. However, access to flucytosine in Africa and Asia, where disease burden...

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Autors principals: Loyse, Angela, Dromer, Françoise, Day, Jeremy, Lortholary, Olivier, Harrison, Thomas S.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797641/
https://ncbi.nlm.nih.gov/pubmed/23788479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt221
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