Metformin use and improved response to therapy in rectal cancer

Locally advanced rectal cancer is commonly treated with chemoradiation prior to total mesorectal excision (TME). Studies suggest that metformin may be an effective chemopreventive agent in this disease as well as a possible adjunct to current therapy. In this study, we examined the effect of metform...

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Detalhes bibliográficos
Main Authors: Skinner, Heath D., Crane, Christopher H., Garrett, Christopher R., Eng, Cathy, Chang, George J., Skibber, John M., Rodriguez-Bigas, Miguel A., Kelly, Patrick, Sandulache, Vlad C., Delclos, Marc E., Krishnan, Sunil, Das, Prajnan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Clinical Cancer Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797563/
https://ncbi.nlm.nih.gov/pubmed/24133632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.54
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