Metformin use and improved response to therapy in rectal cancer

Locally advanced rectal cancer is commonly treated with chemoradiation prior to total mesorectal excision (TME). Studies suggest that metformin may be an effective chemopreventive agent in this disease as well as a possible adjunct to current therapy. In this study, we examined the effect of metform...

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Hlavní autoři: Skinner, Heath D., Crane, Christopher H., Garrett, Christopher R., Eng, Cathy, Chang, George J., Skibber, John M., Rodriguez-Bigas, Miguel A., Kelly, Patrick, Sandulache, Vlad C., Delclos, Marc E., Krishnan, Sunil, Das, Prajnan
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2013
Témata:
Clinical Cancer Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797563/
https://ncbi.nlm.nih.gov/pubmed/24133632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.54
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