Metformin use and improved response to therapy in rectal cancer

Locally advanced rectal cancer is commonly treated with chemoradiation prior to total mesorectal excision (TME). Studies suggest that metformin may be an effective chemopreventive agent in this disease as well as a possible adjunct to current therapy. In this study, we examined the effect of metform...

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Dettagli Bibliografici
Autori principali: Skinner, Heath D., Crane, Christopher H., Garrett, Christopher R., Eng, Cathy, Chang, George J., Skibber, John M., Rodriguez-Bigas, Miguel A., Kelly, Patrick, Sandulache, Vlad C., Delclos, Marc E., Krishnan, Sunil, Das, Prajnan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2013
Soggetti:
Clinical Cancer Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797563/
https://ncbi.nlm.nih.gov/pubmed/24133632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.54
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