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IL-10 Produced by Trophoblast Cells Inhibits Phagosome Maturation Leading to Profound Intracellular Proliferation of Salmonella enterica Typhimurium

INTRODUCTION: Salmonella enterica Typhimurium (ST) is a phagosomal pathogen that can infect placental trophoblast cells leading to abortion and severe maternal illness. It is unclear how the trophoblast cells promote profound bacterial proliferation. METHODS: The mechanism of internalization, intrac...

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Main Authors: Nguyen, Tina, Robinson, Nirmal, Allison, Sarah E., Coombes, Brian K, Sad, Subash, Krishnan, Lakshmi
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797447/
https://ncbi.nlm.nih.gov/pubmed/23834952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2013.06.003
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