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Structural basis for a class of nanomolar influenza A neuraminidase inhibitors
The influenza virus neuraminidase (NA) is essential for the virus life cycle. The rise of resistance mutations against current antiviral therapies has increased the need for the development of novel inhibitors. Recent efforts have targeted a cavity adjacent to the catalytic site (the 150-cavity) in...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797432/ https://ncbi.nlm.nih.gov/pubmed/24129600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02871 |
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