Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein.

A series of mutant human and yeast copper-zinc superoxide dismutases has been prepared, with mutations corresponding to those found in familial amyotrophic lateral sclerosis (ALS; also known as Lou Gehrig's disease). These proteins have been characterized with respect to their metal-binding cha...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Lyons, T J, Liu, H, Goto, J J, Nersissian, A, Roe, J A, Graden, J A, Café, C, Ellerby, L M, Bredesen, D E, Gralla, E B, Valentine, J S
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC37974/
https://ncbi.nlm.nih.gov/pubmed/8901564
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars