Oligodendrocyte/Type-2 Astrocyte Progenitor Cells and Glial-Restricted Precursor Cells Generate Different Tumor Phenotypes in Response to the Identical Oncogenes

Despite the great interest in identifying the cell-of-origin for different cancers, little knowledge exists regarding the extent to which the specific origin of a tumor contributes to its properties. To directly examine this question, we expressed identical oncogenes in two types of glial progenitor...

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Auteurs principaux: Wang, Jun, Bushman, Jared, Wang, Xi, Mayer-Proschel, Margot, Johnson, Mahlon, Noble, Mark
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2013
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797384/
https://ncbi.nlm.nih.gov/pubmed/24133281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0546-13.2013
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