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The emerging and diverse roles of sirtuins in cancer: a clinical perspective
Sirtuins are a highly conserved family of nicotinamide adenine dinucleotide (NAD(+))-dependent protein lysine modifying enzymes with deacetylase, adenosine diphosphateribosyltransferase and other deacylase activities. Mammals have seven sirtuins, namely SIRT1-7. They are key regulators for a wide va...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Dove Medical Press
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797239/ https://ncbi.nlm.nih.gov/pubmed/24133372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S37750 |
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