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The emerging and diverse roles of sirtuins in cancer: a clinical perspective

Sirtuins are a highly conserved family of nicotinamide adenine dinucleotide (NAD(+))-dependent protein lysine modifying enzymes with deacetylase, adenosine diphosphateribosyltransferase and other deacylase activities. Mammals have seven sirtuins, namely SIRT1-7. They are key regulators for a wide va...

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Autori principali: Yuan, Hongfeng, Su, Leila, Chen, Wen Yong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797239/
https://ncbi.nlm.nih.gov/pubmed/24133372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S37750
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