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Impact of host and virus genome variability on HCV replication and response to interferon

Since the discovery of hepatitis C virus (HCV), treatment has proven difficult and the regimen of pegylated interferon-α and ribavirin is only effective for half of patients. Evidence suggests that host and viral genome variations play a role in either viral clearance or persistence. Powerful genomi...

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Detalhes bibliográficos
Main Authors: Schweitzer, Cameron J, Liang, T Jake
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797205/
https://ncbi.nlm.nih.gov/pubmed/23835049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2013.06.005
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