Insulin and IGF1 enhance IL-17-induced chemokine expression through a GSK3B-dependent mechanism: a new target for melatonin's anti-inflammatory action

Obesity is a chronic inflammation with increased serum levels of insulin, insulin-like growth factor 1 (IGF1), and interleukin-17 (IL-17). The objective of this study was to test a hypothesis that insulin and IGF1 enhance IL-17-induced expression of inflammatory chemokines/cytokines through a glycog...

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Autori principali: Ge, Dongxia, Dauchy, Robert T., Liu, Sen, Zhang, Qiuyang, Mao, Lulu, Dauchy, Erin M., Blask, David E., Hill, Steven M., Rowan, Brian G., Brainard, George C., Hanifin, John P., Cecil, Kate S., Xiong, Zhenggang, Myers, Leann, You, Zongbing
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797167/
https://ncbi.nlm.nih.gov/pubmed/24033914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jpi.12084
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