MUC1 Regulates Expression of Multiple microRNAs Involved in Pancreatic Tumor Progression, Including the miR-200c/141 Cluster

MUC1 is a transmembrane glycoprotein that modulates transcription via its cytoplasmic domain. We evaluated the capacity of MUC1 to regulate the global transcription of microRNAs in pancreatic cancer cells expressing MUC1. Results indicated that MUC1 regulated expression of at least 103 microRNAs. We...

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Detalhes bibliográficos
Main Authors: Mohr, Ashley M., Bailey, Jennifer M., Lewallen, Michelle E., Liu, Xiang, Radhakrishnan, Prakash, Yu, Fang, Tapprich, William, Hollingsworth, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797065/
https://ncbi.nlm.nih.gov/pubmed/24143167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073306
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