Structural and Mechanistic Insight into DNA Unwinding by Deinococcus radiodurans UvrD

DNA helicases are responsible for unwinding the duplex DNA, a key step in many biological processes. UvrD is a DNA helicase involved in several DNA repair pathways. We report here crystal structures of Deinococcus radiodurans UvrD (drUvrD) in complex with DNA in different nucleotide-free and bound s...

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Bibliografiska uppgifter
Huvudupphovsmän: Stelter, Meike, Acajjaoui, Samira, McSweeney, Sean, Timmins, Joanna
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797037/
https://ncbi.nlm.nih.gov/pubmed/24143224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077364
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