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Phosphorylation of FOXP3 by LCK Downregulates MMP9 Expression and Represses Cell Invasion

Forkhead Box P3 (FOXP3) is a member of the forkhead/winged helix family of the transcription factors and plays an important role not only as a master gene in T-regulatory cells, but also as a tumor suppressor. In this study, we identified lymphocyte-specific protein tyrosine kinase (LCK), which corr...

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Detalhes bibliográficos
Main Authors: Nakahira, Kumiko, Morita, Akihiro, Kim, Nam-Soon, Yanagihara, Itaru
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796550/
https://ncbi.nlm.nih.gov/pubmed/24155921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077099
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