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Physiological regulation of tau phosphorylation during hibernation

The microtubule-associated protein tau is abnormally hyperphosphorylated in the brains of individuals with Alzheimer disease and other tauopathies, and is believed to play a critical role in the pathogenesis of these diseases. While the mechanisms leading to abnormal tau phosphorylation remain elusi...

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Detalhes bibliográficos
Main Authors: Su, Bo, Wang, Xinglong, Drew, Kelly L., Perry, George, Smith, Mark A., Zhu, Xiongwei
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796382/
https://ncbi.nlm.nih.gov/pubmed/18284615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05294.x
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