Metabolite Profile Analysis Reveals Functional Effects of 28-Day Vitamin B-6 Restriction on One-Carbon Metabolism and Tryptophan Catabolic Pathways in Healthy Men and Women(1)(2)(3)

Suboptimal vitamin B-6 status, as reflected by low plasma pyridoxal 5′-phosphate (PLP) concentration, is associated with increased risk of vascular disease. PLP plays many roles, including in one-carbon metabolism for the acquisition and transfer of carbon units and in the transsulfuration pathway....

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Main Authors: da Silva, Vanessa R., Rios-Avila, Luisa, Lamers, Yvonne, Ralat, Maria A., Midttun, Øivind, Quinlivan, Eoin P., Garrett, Timothy J., Coats, Bonnie, Shankar, Meena N., Percival, Susan S., Chi, Yueh-Yun, Muller, Keith E., Ueland, Per Magne, Stacpoole, Peter W., Gregory, Jesse F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Nutrition 2013
Assuntos:
Genomics, Proteomics, and Metabolomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796343/
https://ncbi.nlm.nih.gov/pubmed/23966327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.113.180588
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