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Protection from oxidative and electrophilic stress in the Gsta4-null mouse heart

4-hydroxynonenal (4-HNE) mediates many pathological effects of oxidative and electrophilic stress and signals to activate cytoprotective gene expression regulated by NF-E2-related factor 2 (Nrf2). By exhibiting very high levels of 4-HNE-conjugating activity, the murine glutathione transferase alpha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Beneš, Helen, Vuong, Mai K., Boerma, Marjan, McElhanon, Kevin E., Siegel, Eric R., Singh, Sharda P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796146/
https://ncbi.nlm.nih.gov/pubmed/23690225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12012-013-9215-1
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