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Deficiency of Kruppel-like factor KLF4 in mammary tumor cells inhibits tumor growth and pulmonary metastasis and is accompanied by compromised recruitment of myeloid-derived suppressor cells

Increasing evidence indicates that myeloid-derived suppressor cells (MDSCs) negatively regulate immune responses during tumor progression, inflammation and infection. However, the underlying molecular mechanisms of their development and mobilization remain to be fully delineated. Kruppel-like factor...

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Detalhes bibliográficos
Main Authors: Yu, Fang, Shi, Ying, Wang, Junfeng, Li, Juan, Fan, Daping, Ai, Walden
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796127/
https://ncbi.nlm.nih.gov/pubmed/23737434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28302
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