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Concomitant loss of EAF2/U19 and Pten synergistically promotes prostate carcinogenesis in the mouse model

Multiple genetic alterations are associated with prostate carcinogenesis. Tumor-suppressor genes phosphatase and tensin homolog deleted on chromosome 10 (Pten) and androgen upregulated gene 19 (U19), which encodes ELL-associated factor 2 (EAF2), are frequently inactivated or downregulated in advance...

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Detalhes bibliográficos
Main Authors: Ai, J, Pascal, LE, O’Malley, KJ, Dar, JA, Isharwal, S, Qiao, Z, Ren, B, Rigatti, LH, Dhir, R, Xiao, W, Nelson, JB, Wang, Z
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796117/
https://ncbi.nlm.nih.gov/pubmed/23708662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.190
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