Opposite Feedbacks in the Hippo Pathway for Growth Control and Neural Fate

Signaling pathways are re-used for multiple purposes in plant and animal development. The Hippo pathway in mammals and Drosophila coordinates proliferation and apoptosis via the co-activator and oncogene, YAP/Yorkie (Yki), which is homeostatically regulated through negative feedback. In the Drosophi...

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Main Authors: Jukam, David, Xie, Baotong, Rister, Jens, Terrell, David, Charlton-Perkins, Mark, Pistillo, Daniela, Gebelein, Brian, Desplan, Claude, Cook, Tiffany
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796000/
https://ncbi.nlm.nih.gov/pubmed/23989952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1238016
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