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Cognitive decline in prodromal Huntington Disease: Implications for Clinical Trials

Controversy exists regarding the feasibility of preventive clinical trials in prodromal Huntington disease (HD). A primary limitation is a lack of outcome measures for persons with the gene mutation who have not yet been diagnosed with HD. Many longitudinal studies of cognitive decline in prodromal...

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Detalhes bibliográficos
Main Authors: Paulsen, Jane S., Smith, Megan M., Long, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795884/
https://ncbi.nlm.nih.gov/pubmed/23911948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2013-305114
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