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Tissue-specific Leptin promoter DNA methylation is associated with maternal and infant perinatal factors

Leptin a regulator of body weight is involved in reproductive and developmental functions. Leptin promoter DNA methylation (LEP) regulates gene expression in a tissue-specific manner and has been linked to adverse pregnancy outcomes. In non-pathologic human pregnancies, we assessed LEP methylation,...

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Detalhes bibliográficos
Main Authors: Lesseur, Corina, Armstrong, David A., Paquette, Alison G., Koestler, Devin C., Padbury, James F., Marsit, Carmen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795868/
https://ncbi.nlm.nih.gov/pubmed/23911897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2013.07.024
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