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Inhibition of breast cancer metastasis by resveratrol-mediated inactivation of tumor-evoked regulatory B cells

We previously reported that tumor-evoked regulatory B cells (tBregs) play an essential role in breast cancer lung metastasis by inducing TGFβ-dependent conversion of metastasis-promoting FoxP3(+) Tregs. Here we show that resveratrol (RSV), a plant-derived polyphenol, at low and non-cytotoxic doses f...

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Dettagli Bibliografici
Autori principali: Lee-Chang, Catalina, Bodogai, Monica, Martin-Montalvo, Alejandro, Wejksza, Katarzyna, Sanghvi, Mitesh, Moaddel, Ruin, de Cabo, Rafael, Biragyn, Arya
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795852/
https://ncbi.nlm.nih.gov/pubmed/24043896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300606
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