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Interleukin-1β Inhibits Insulin Signaling and Prevents Insulin-Stimulated System A Amino Acid Transport in Primary Human Trophoblasts

Interleukin-1β (IL-1β) promotes insulin resistance in tissues such as liver and skeletal muscle; however the influence of IL-1β on placental insulin signaling is unknown. We recently reported increased IL-1β protein expression in placentas of obese mothers, which could contribute to insulin resistan...

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Autori principali: Aye, Irving L. M. H., Jansson, Thomas, Powell, Theresa L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795822/
https://ncbi.nlm.nih.gov/pubmed/23891856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2013.07.013
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