TNF, Acting through Inducibly Expressed TNFR2, Drives Activation and Cell Cycle Entry of c-kit(+) Cardiac Stem Cells in Ischemic Heart Disease

TNF, signaling through TNFR2, has been implicated in tissue repair, a process that in the heart may be mediated by activated resident cardiac stem cells (CSCs). The objective of our study is to determine whether ligation of TNFR2 can induce activation of resident CSCs in the setting of ischemic card...

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Auteurs principaux: Al-Lamki, Rafia S., Lu, WanHua, Wang, Jun, Yang, Jun, Sargeant, Timothy J., Wells, Richard, Suo, Chenqu, Wright, Penny, Goddard, Martin, Huang, Qunhua, Lebastchi, Amir H., Tellides, George, Huang, Yingqun, Min, Wang, Pober, Jordan S., Bradley, John R.
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795817/
https://ncbi.nlm.nih.gov/pubmed/23712715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1433
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