Deferred Pre-Emptive Switch from Calcineurin Inhibitor to Sirolimus Leads to Improvement in GFR and Expansion of T Regulatory Cell Population: A Randomized, Controlled Trial

BACKGROUND: Measures to prevent chronic calcineurin inhibitor (CNI) toxicity have included limiting exposure by switching to sirolimus (SIR). SIR may favorably influence T regulator cell (T(reg)) population. This randomized controlled trial compares the effect of switching from CNI to SIR on glomeru...

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Hlavní autoři: Bansal, Dinesh, Yadav, Ashok K., Kumar, Vinod, Minz, Mukut, Sakhuja, Vinay, Jha, Vivekanand
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795731/
https://ncbi.nlm.nih.gov/pubmed/24146762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075591
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