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Amide proton exchange of a dynamic loop in cell extracts

Intrinsic rates of exchange are essential parameters for obtaining protein stabilities from amide (1)H exchange data. To understand the influence of the intracellular environment on stability, one must know the effect of the cytoplasm on these rates. We probed exchange rates in buffer and in Escheri...

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Bibliographic Details
Main Authors: Smith, Austin E, Sarkar, Mohona, Young, Gregory B, Pielak, Gary J
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795490/
https://ncbi.nlm.nih.gov/pubmed/23904228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2318
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